July 21st, 2018

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Dietary Intake and Body Composition in New Users of the Injectable Contraceptive Depot-Medroxyprogesterone Acetate During the First Year of Use
Authors:  Priscilla de Nazaré Silva dos Santos, Ph.D., M. Valeria Bahamondes, M.D., Ph.D., Waleska Oliveira Modesto, Ph.D., Luis Bahamondes, M.D., Ph.D., and Arlete Maria dos Santos Fernandes, M.D., Ph.D.
  OBJECTIVE: To evaluate dietary intake and body composition in new users of the injectable contraceptive depot-medroxyprogesterone acetate (DMPA).

STUDY DESIGN: A non-randomized clinical trial. Healthy women (28 DMPA users and 24 copper intrauterine device [IUD] users) were paired for age (±1 year) and body mass index (BMI) (kg/m2) (±1). Weight, lifestyle habits, and dietary intake recorded using a 3-day food recall form were evaluated at three-monthly intervals during the first year of use of the method. Body composition was assessed at baseline and at 12 months by dual-energy x-ray absorptiometry.

RESULTS: Mean age was 29.6 and 28.6 years in DMPA and IUD users, respectively, while BMI was 23.9 and 24.5 kg/m2, respectively. An increase of approximately 12% was found in calorie intake (kilocalories/24 h) and in all the macronutrients of the diet in the DMPA group from the third month onwards. There was increase in total lean mass (p<0.046) in the DMPA group and no statistically significant difference in body weight between the groups. No association was found between dietary intake and weight gain.

CONCLUSION: When initiating use, new DMPA users should be counseled regarding possible changes in dietary intake.
Keywords:  body composition, contraception, dietary intake, medroxyprogesterone acetate
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