July 21st, 2018

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Comparison of in Vitro Fertilization Outcomes in Unoperated Unilateral/Bilateral Endometriomas with Operated Unilateral/Bilateral Endometriomas
Authors:  Yigit Cakiroglu, M.D., Emek Doger, M.D., Fisun Vural, M.D., Sule Yildirim Kopuk, M.D., and Birol Vural, M.D.
  OBJECTIVE: To collect the IVF outcomes from patients with endometriomas who were not treated surgically and compare the results with those of women who were treated surgically for uni/bilateral endometriomas.

STUDY DESIGN: The records of 114 patients with a diagnosis of endometriosis were classified into 4 groups: no surgery for unilateral endometrioma (Group 1), no surgery for bilateral endometrioma (Group 2), surgery for unilateral endometrioma (Group 3), and surgery for bilateral endometrioma (Group 4). In all groups, gonadotropin stimulation was initiated according to age, body mass indices, and number of antral follicles.

RESULTS: The number of antral follicles was statistically significantly higher in Group 1 as compared to Groups 2–4. The data revealed a similar pattern for the number of follicles on hCG day as well as the number of metaphase II (MII) oocytes and embryos, with Group 1 showing statistically significantly higher results than Groups 3 and 4 and Group 2 showing statistically significantly higher results than Group 4. The number of retrieved oocytes was significantly lower in group 4 than in the other groups. The numbers of pregnancies, missed abortus, biochemical pregnancies, and deliveries were comparable in all groups.

CONCLUSION: The data imply that surgically untreated unilateral endometrioma patients have higher numbers of antral follicles, follicles on hCG day, retrieved oocytes, MII oocytes, and embryos. The number of pregnancies and deliveries was similar. There was no correlation between the size of the endometriomas and the pregnancy rates.
Keywords:  endometrioma, endometriosis, gynecologic surgery, in vitro fertilization
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