July 21st, 2018

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Successful Live Birth from Oocytes Cryopreserved for 11 Years: A Case Report
Authors:  Lauren Zakarin Safier, M.D., and Mark V. Sauer, M.D.
BACKGROUND: Oocyte cryopreservation, or egg freezing, was considered an experimental technology until 2012. Freezing methods continue to evolve and improve, but, to date, most patient outcomes are largely limited to women who return in the short-term. Longer term freezing results are rarely reported, as many patients ultimately discard their stored oocytes or are currently still storing them.

CASE: A 41-year-old woman successfully conceived from oocytes cryopreserved for over 11 years. She had originally sought fertility preservation advice secondary to concerns over a large persistent pituitary macroadenoma that had been partially removed in her teens and continued to present difficulties despite medical management. Seven thawed oocytes produced a single normal blastocyst that was transferred, resulting in the viable pregnancy.

CONCLUSION: This case illustrates the clinical utility of offering oocyte freezing to patients at risk of losing their fertility and the potential for long-term storage with successful outcome.
Keywords:  assisted reproductive techniques; cryopreservation; egg, unfertilized; oocytes; ovum; reproduction technology, assisted
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