October 18th, 2018

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IVF Treatment Should Not Be Postponed for Patients After Excision of Ovarian Endometrioma with Normal Basal FSH Concentration: A Retrospective Study
Authors:  Yue Lin, M.S., Yizuo Chen, M.S., Xuefeng Huang, M.D., Jinju Lin, M.M., Peiyu Wang, M.M., and Junzhao Zhao, M.D.
  OBJECTIVE: To compare treatment outcome in patients after excision of ovarian endometrioma with normal follicle-stimulating hormone (FSH) concentrations versus their counterparts.

STUDY DESIGN: We retrospectively evaluated 143 controlled ovarian hyperstimulation (COH) cycles, including 76 cycles after previous excision of ovarian endometrioma (group I) and 67 cycles with male factor infertility (group II) from January 2008 to January 2013. All patients’ basal FSH level was <10 IU/L.

RESULTS: The patients’ characteristics and mostly the IVF treatment outcome parameters between the 2 groups had no significant differences. However, the number of retrieved oocytes was significantly higher in group II than in group I (p=0.02), and the number of retrieved oocytes significantly decreased in patients <1 year and 2–3 years after excision of ovarian endometrioma (p= 0.028, group II vs. group I1; p=0.005, group II vs. group I3; p=0.04, group I2 vs. group I3). The postoperative period independently contributed to the recombinant FSH (rFSH) dosage in a COH cycle (p=0.018), and the rFSH dosage significantly increased in patients >4 years after excision of ovarian endometrioma (p=0.000, group II vs. group I5; p= 0.001, group I1 vs. group I5; p=0.012, group I2 vs. group I5; p=0.001, group I3 vs. group I5; and p=0.004, group I4 vs. group I5).

CONCLUSION: IVF treatment should not be delayed in patients after excision of ovarian endometrioma with normal basal FSH concentrations.
Keywords:  endometrioma; endometriosis; follicle stimulating hormone; FSH; in vitro fertilization; ovulation induction
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