October 18th, 2018

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Negative Pap Smear, Positive HPV: What Does It Mean?
Authors:  Sarina Schrager, M.D., M.S., and Lindsey Yanke, M.D.
  New cervical cancer screening guidelines recommend that women over age 30 have a Pap smear and HPV test every 5 years. This retrospective study looks at the colposcopy results of women seen at the University of Wisconsin Department of Family Medicine who had a negative Pap smear and positive HPV test between November 2012 and January 2015. A total of 81 charts were reviewed, and only 6 (2.4%) had an abnormal biopsy, with 4 women having CIN I and only 2 having CIN II/III. To find those 2 women, it took 45 biopsies and 54 endocervical curettages.
Keywords:  cancer screening, cancer screening tests, cervical cancer, cervical cancer screening guidelines, cervical intraepithelial neoplasia, cervix cancer, colposcopy, early detection of cancer, early diagnosis of cancer, human papillomavirus, human papillomavirus 16, HPV, Pap smear, Pap test, Papanicolaou smear, uterine cervical neoplasms
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