December 19th, 2018

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Title:
Heavy Smoking Responsible for the Reduction of Antral Follicles and Lower Recovery of Oocytes in Assisted Reproduction Cycles: A Case Report
Authors:  Ana Karina Bartmann, M.D., Ph.D., Victor César de Paula S. Nascimento, B.Sc., Pérola Rafaella Cedano Godoy P. de Souza, M.D., and Heloisa Gomes, M.D.
 
BACKGROUND: As is widely known, smoking negatively influences fertility. Two mechanisms are accountable for this effect: oxidative stress and DNA damage, which lead to the toxicity of the substances present in tobacco.

CASE: A 38-year-old woman presented to the clinic for primary infertility. She had regular periods and had not used any contraceptive method for 10 years. She presented antral follicle counts of 5 and 9 in each treatment attempt but just 1 and 3 oocytes, respectively, due to age or high tobacco load. Both in vitro fertilization attempts were unsuccessful.

CONCLUSION: This case shows the great negative influence that tobacco has on fertility. It demonstrates the difficulty in attaining pregnancy in a treatment-compliant patient.
Keywords:  assisted reproductive technologies, cigarette smoking, in vitro fertilization, infertility, smoking, tobacco smoking
   
   
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