September 27th, 2020

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Title:
Efficacy of in Vitro Fertilization in Treating Infertility Caused by Severe Vaginismus: A Case Series
Authors:  Ying-Wen Wang, M.D., Pei-Yun Lin, M.D., Yi-Chi Lin, B.S., and Kuo-Chung Lan, M.D., Ph.D.
  OBJECTIVE: To retrospectively review the demographic and clinical characteristics of women with infertility caused by severe vaginismus and their outcomes after in vitro fertilization (IVF).

STUDY DESIGN: In this retrospective case series, 13 women with infertility related to severe vaginismus treated with IVF between 1998 and 2017 at our hospital were included. Their demographic characteristics, IVF cycles, average number of mature oocytes harvested, embryo quality, pregnancy outcomes, and methods of delivery were analyzed.

RESULTS: The mean duration of infertility before intervention was 5.3 years, at an average age of 34.5 years. They received an average of 2.1 IVF cycles, and the mean number of mature oocytes harvested was 6.3. Twelve of the 13 women became pregnant after IVF treatment. The pregnancy rate was 51.9% per cycle. Most of these women chose cesarean section for delivery.

CONCLUSION: Although a literature review indicated that cognitive behavioral therapy was the mainstay of treatment for vaginismus, IVF may yield satisfactory outcomes in women with infertility caused by severe vaginismus.
Keywords:  anxiety/complications; assisted reproductive techniques; cognitive behavioral therapy; genito-pelvic pain/penetration disorder; in vitro fertilization; intravaginal insemination; pain/etiology; sexual behavior/psychology; sexual dysfunction; sexual dysfunctions, psychological; vaginal diseases; vaginismus
   
   
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