October 24th, 2020

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Title:
Twin Pregnancy with Coexistence of a Healthy Fetus and a Complete Hydatidiform Mole: A Case Report
Authors:  Elena M. Hartmann, M.D., Ph.D., Monika Rehn, M.D., Achim Wöckel, M.D., and Karen Ernestus, M.D.
 
BACKGROUND: The occurrence of a twin pregnancy with a viable fetus and a complete hydatidiform mole is a rare event and bears the risk of several potentially serious fetal and/or maternal complications.

CASE: We report an unusual case of a twin pregnancy with a viable fetus and a complete hydatidiform mole that proceeded without complications and resulted interm birth of a healthy infant. The reported pregnancy occurred after natural conception without medical assistance. A cesarean section was performed in the 39th week of gestation and resulted in the delivery of a healthy female neonate and a normal-appearing placenta at the posterior uterine wall. Furthermore, at the anterior uterine wall, without connection to the previously mentioned placenta, a vesicular mass was found and curetted. Pathological examination of the latter revealed a complete hydatidiform mole. The infant and mother did well, with decreasing serial maternal serum β-hCG levels and no evidence of a persistent gestational trophoblastic disease in 2 years of follow-up.

CONCLUSION: The present report shows that, rarely, twin pregnancy with a viable fetus and a complete hydatidiform mole can occur with an uncomplicated pregnancy as well as term birth and without subsequent complications for mother and infant.
Keywords:  complete mole, fetus, gestational trophoblastic disease, healthy co-twin, hydatidiform mole, molar pregnancy, pregnancy, pregnancy complications, pregnancy outcome, twin pregnancy, uterine neoplasms
   
   
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