|
||||||||||||||||||||
Title: |
False Positive ROM Plus Result Associated with Cervical Herpes Simplex Virus: A Case Report | |||||||||||||||||||
| Authors: | Tiffany Swanson, D.O., Joshua Leichty, D.O., Leah Kurth, D.O., and Gregory Goyert, M.D. | |||||||||||||||||||
|
BACKGROUND: Inaccurate diagnosis of preterm prelabor rupture of membranes (PPROM) can lead to adverse fetal and maternal outcomes. The ROM Plus Rupture of Membranes Test, a monoclonal/polyclonal immunoassay test, aids in the diagnosis but has the potential for false positive results. CASE: A 25-year-old wom-an at 21 weeks’ gestation presented with symptoms concerning for previable pre-labor rupture of membranes. ROM Plus was reported as positive in the setting of absent ferning and normal amniotic fluid index. She was discharged home with suspicion for a false positive result and was later diagnosed with herpes simplex virus infection of the cervix. CONCLUSION: Preterm prelabor rupture of membranes can have serious consequences and should be accurately diagnosed. Further research is needed to assess the potential association of herpes simplex virus with a false positive ROM Plus test result. |
||||||||||||||||||||
| Keywords: | amniotic fluid index, false positive, ferning, herpes simplex virus, IGFBP-1, point-of-care immunoassay, pooling, premature rupture of membranes, ROM Plus®, rupture of membranes | |||||||||||||||||||
| Acrobat Reader 7.0 is recommended to properly view and print the article.
Reader can be downloaded from  |
||||||||||||||||||||
