June 22nd, 2018

Volume 62
Number 4
Lawrence D. Devoe, M.D.

 Clinical Perspectives
Amanda J. Adeleye, M.D., and Mark V. Sauer, M.D.
This review examines the complex medical issues that physicians must consider when treating transgender patients who are considering their reproductive options.

Andrew R. Orr, B.S., and Mark Martens, M.D.
Melioidosis, a significant cause of mortality in endemic areas, has the potential to occupy new niches in the modern era, thus necessitating clearer treatment protocols for those patients most at risk, including pregnant women.

 Original Articles
Karen E. Elkind-Hirsch, M.Sc., Ph.D., Martha Paterson, M.D., Ericka Seidemann, M.S., and Hanh Gutowski, R.N.
While body weight has no impact on reduction of hyperandrogenism, obesity plays a significant role on the metabolic impact of contraceptive therapy in women with polycystic ovary syndrome.

Deborah Gavanier, M.D., Fabienne Allias, M.D., Cyril Huissoud, M.D., Ph.D., Touria Hajri, M.S., François Golfier, M.D., Ph.D., and Jérôme Massardier, M.D.
Placental mesenchymal dysplasia is an uncommon disease that is associated with obstetric and neonatal complications and can be detected early in pregnancy by ultrasound.

Edward D. Tarnawa, M.D., John A. Schnorr, M.D., John Baatz, Ph.D., and Christopher J. Robinson, M.D., MSCR
Circadian gene and protein expression is present in human granulosa cells.

Gerard G. Nahum, M.D., FACOG, FACS, Andrew M. Kaunitz, M.D., FACOG, Eeva Lukkari-Lax, M.D., Ph.D., Thomas Schmelter, Ph.D., and Kimberly Rosen, M.D.
With LNG-IUS 12 use, the frequency of ovarian cysts was minimally increased as compared to baseline. The vast majority of cysts were not clinically significant.

Li-Li Zhuang, M.D., Cui-Fang Hao, M.D., Ning Zhang, M.D., Xiao-Yan Liu, M.B., Li Ge, M.B., and Jin-Long Ma, M.D.
Patients with higher thyroid-stimulating hormone and thyroid autoantibodies had a higher miscarriage rate; thyroid autoantibodies did not influence the clinical pregnancy rate of the first in vitro fertilization cycles.

Nikolaos Vlachadis, M.D., D.M.D., M.P.H., M.Sc., D.Sc., Vasileios Tsamadias, B.Sc., Nikolaos Vrachnis, M.D., Ph.D., Konstantinos Hatziveis, M.D., Ph.D., Evaggelia Kouskouni, M.D., Ph.D., and Emmanuel Economou, Pharm.D., Ph.D.
PECAM1-G allele, especially in combination with P-selectin-C allele, may be associated with implantation failure after in vitro fertilization in women with unexplained infertility.

Ayse Arvas Ulug, M.D., Ph.D., Meric Karacan, M.D., Murat Ulug, Ph.D., Ziya Cebi, M.D., and Teksen Camlibel, M.D., Ph.D.
The outcome of a 20-second delay of the embryo transfer catheter in the uterine cavity following blastocyst transfer is similar to that of immediate withdrawal of the catheter.

Shilpa Bhandari, M.D., Pallavi Agrawal, M.D., Ishita Ganguly, M.D., Aparna Singh, M.D., and Mohit Bhandari, M.D.
Irregular menses secondary to anovulation among morbidly obese women desiring pregnancy could potentially be viewed as an additional indication for bariatric surgery.

Dotun Ogunyemi, M.D., John Robin Boulet, Ph.D., and Paul Sobolewski, M.D.
International medical graduates comprise 15% of the practicing obstetrician-gynecologists in the U.S.––lower than for all physicians––with variations in residency training, practice patterns, and board certification

Maria Antonietta Castaldi, M.D., Lavinia Mosca, M.D., Giulio Toro, M.D., Nicola Colacurci, M.D., Giuseppe Signoriello, M.D., Ph.D., and Luigi Cobellis, M.D., Ph.D.
Laparoscopic myomectomy with 2 operative trocars represents a safe and valid surgical approach in selected patients, while the 3-trocar technique remains the best choice for large and awkwardly located myomas.

Yasemin Cekmez, M.D., Vakkas Korkmaz, M.D., Aslı Çakır, M.D., Ahmet Göçmen, M.D., Yusuf Ergün, M.D., and Serdar Gülsen, M.D.
Metoclopramide exposure, especially in high doses, may cause abortion and should be recommended for use during pregnancy only when the benefit outweighs the risk.

 Case Reports
Man Hin Menelik Lee, M.B.B.S., MRCOG, FHKCOG, FHKAM(OG), and Tomoko Matsuzono, M.B.B.S., MRCOG, FHKCOG, FHKAM(OG)
The authors present 2 cases of concomitant intrauterine morcellation of submucosal fibroids followed by second generation radiofrequency bipolar endometrial ablation in the management of menorrhagia.

Chinedu Nwabuobi, M.D., M.S., James Towner, M.D., Mary Towner, M.D., and Neil Seligman, M.D., M.S.
We discuss the obstetric and neurosurgical management of a gravid patient with acute onset of hydrocephalus from growth of a subependymal giant-cell astrocytoma.

Alexandra Wilson, M.S., and Richard P. Porreco, M.D.
Massive fetal ascites without polyhydramnios can be an isolated finding associated with jejunal atresia and apple peel deformity.

Andrew B. Pressman, M.D., and Jeffery S. Ditkoff, M.D.
This case demonstrates the difficulties in diagnosis and risk of hemorrhage after methotrexate administration for a cervical ectopic pregnancy with a younger gestational age and smaller gestational sac than has been reported previously.

Shadi Rezai, M.D., Andres Molina, B.S., Hasan Nezam, M.D., Ray Mercado, D.O., and Cassandra Henderson, M.D.
The V-Go insulin infusion device appears to be a well-tolerated alternative to an insulin pump for the infusion of subcutaneous insulin during pregnancy.

Natasha Gupta, M.D., Josef Blankstein, M.D., and Richard Trester, M.D.
An abdominal pregnancy or a chronic ectopic pregnancy can go undiagnosed and present as recurrent tubo-ovarian abscesses, caused by infection of the conceptus and necessitating definitive surgical treatment with hysterectomy.

Mohammad S. Mahmoud, M.D.
The removal of Essure microinserts long after insertion time is feasible using a combined laparoscopic and hysteroscopic approach.

Adam V. Levy, M.D., Neetu Cheema, M.D., and Vani Dandolu, M.D.
A pregnancy termination at 19 weeks’ gestation was complicated by the fetal spine having penetrated into the cervical stroma, necessitating follow-up surgery to recover it.

Anca A. Simionescu, M.D., Ph.D., and Nicoleta Berbec, M.D., Ph.D.
The authors present a case of postpartum hemorrhage due to a missed diagnosis of acute promyelocytic leukemia in pregnancy despite medical monitoring.

 Checklist for Authors


The opinions and statements in this journal are those of the authors and are not attributable to the sponsor, publisher, editors or editorial board of JRM. Product dosages, indications and methods of use referred to in the papers and discussions reflect the authors' clinical experience or are derived from other professional sources.