June 22nd, 2018

Volume 62
Number 3
Lawrence D. Devoe, M.D.

 Clinical Perspectives
Javine McLaughlin, M.D., and Lawrence D. Devoe, M.D.
The authors present a review of the safety and efficacy of administering various prostaglandin formulations for cervical ripening.

 Original Articles
Elie Hobeika, M.D., Shaveta Malik, M.D., Michael L. Traub, M.D., Seleshi Demissie, Dr.P.H., and Eric S. Knochenhauer, M.D.
FSH/hCG co-trigger does not increase pregnancy rates in patients undergoing gonadotropin/IUI cycles and should be used with caution due to the possible increase in the risk of multiples. This protocol, however, might be beneficial in patients with diminished ovarian response to gonadotropins.

Glauco Baiocchi, M.D., Ph.D., Maria Dirlei Begnami, M.D., Ph.D., Michael Jenwei Chen, M.D., Elza Mieko Fukazawa, M.D., Ph.D., Levon Badiglian-Filho, M.D., Ph.D., Antonio Cassio Assis Pellizzon, M.D., Ph.D., Fernando Augusto Soares, M.D., Ph.D., and Ademar Lopes, M.D., Ph.D.
HER-2 expression is associated with response to radiotherapy in cervical cancer.

Patricia Rekawek, M.D., Frederick Friedman, Jr., M.D., Bertille Gaigbe-Togbe, M.D., Joseph Lee, B.A., and Alan B. Copperman, M.D.
Transfer of an embryo with a suboptimal morphology score during an in vitro fertilization cycle is not associated with negative obstetric outcome.

María Inés Bianconi, M.D., Silvina Otero, M.D., Claudio Storino, M.D., and Gustavo Jankilevich, M.D.
The convenient oral route of administration and the proven efficacy make capecitabine a drug to be taken into account for gestational trophoblastic neoplasia patients showing resistance to standard regimens.

Miriam S. Krause, M.D., Kristine Holthouser, M.D., Jeremy T. Gaskins, Ph.D., Henry C. L. Bohler, Jr., M.D., and Steven T. Nakajima, M.D.
The Bayes classifier can be used to assess the risk for a pregnancy being ectopic rather than intrauterine based on early measurement of hCG levels.

Seung-Hyuk Shim, M.D., Ph.D., Sun Joo Lee, M.D., Ph.D., Seung Woo Yang, M.D., Ji Young Lim, M.D., Soo-Hyun Cho, M.D., Wook Youn Kim, M.D., Ph.D., Hee Sun Kim, M.D., Ph.D., and Soo-Nyung Kim, M.D., Ph.D.
The electrosurgical conization method using a right-angled, triangular loop could reduce postoperative hemorrhage and positive resection margins as compared to the method using a ring-shaped loop.

Quan Huang, M.D., Jian Liu, Ph.D., Tenghui Chen, Ph.D., Lei Li, Ph.D., Lu Wang, Ph.D., and Yelin Wu, Ph.D.
Both ductal and lobular breast cancers harbor subtype-specific programs that are aberrantly upregulated, thereby suggesting that distinct therapeutic targets may need to be pursued for devising efficacious clinical treatment.

Sen-lin Shi, Ph.D., Zhao-feng Peng, Ph.D., Gui-dong Yao, Ph.D., Hai-xia Jin, Ph.D., Wen-yan Song, Ph.D., Hong-yi Yang, M.D., and Ying-pu Sun, Ph.D.
Retrieving an adequate number of mature oocytes is the key to the prevention of having no embryos transferred in assisted reproductive technology.

Bo Xu, M.M., Haidong Cheng, M.M., Xiaotian Li, M.D., and Nebhani Mouna, B.M.
Previous lower segment cesarean section, cephalopelvic disproportion, and intrauterine growth restriction were found to be the 3 most common indications for cesarean section.

Jae Eun Shin, M.D., Jong Chul Shin, M.D., Sa Jin Kim, M.D., Young Lee, M.D., Soo Ah Im, M.D., and In Yang Park, M.D.
Magnetic resonance imaging contributes to ultrasound in the diagnosis of CNS anomalies, especially for cases of indefinite diagnosis and ventriculomegaly by ultrasound.

Aytekin Tokmak, M.D., Ali Irfan Guzel, M.D., Gürhan Güney, M.D., Umit Tasdemir, M.D., Coskun Umit, M.D., and Nafiye Yilmaz, M.D.
Obesity adversely affects pregnancy rates in women with polycystic ovary syndrome who undergo ovulation induction cycles; obese patients with polycystic ovary syndrome should be advised to reduce their weight before treatment.

Huiqin Xue, M.D., Lan Ma, M.B.B.S., Jinjie Xue, M.D., Xiayu Sun, M.B.B.S., Ming Li, M.B.B.S., Hongyong Lu, M.M., Yan Zhou, M.B.B.S., Yuezhen Guo, M.B.B.S., Yuping Zhang, M.M., and Jigeng Bai, M.M.
A reduced expression level of LEFTY1 was identified in women with missed abortion, which may result in a dysregulation of TGF-β signaling.

Teppei Takeshima, M.D., Yasushi Yumura, M.D., Ph.D., Shinnosuke Kuroda, M.D., Yoshitake Kato, M.D., Kazumi Noguchi, M.D., Ph.D., and Akira Iwasaki, M.D., Ph.D.
Varicocele repair can be considered in patients with nonobstructive azoospermia and clinical varicoceles.

Mansour Almansour, Ph.D., Qais Jarrar, M.Sc., Abdelkader Battah, Ph.D., and Bashir Jarrar, Ph.D.
Silver nanoparticles could have a harmful impact on testicular tissues and the spermatogenic process that could affect fertility and reproduction.

Ji Yeon Lee, M.D., and Jong Yun Hwang, M.D., Ph.D.
The expression of fetal testicular genes Tssk2, Ovol1, and Mea1 in the group exposed to 1.765 GHz microwave in utero was downregulated.

Kristin Van Heertum, M.D., Stephen Somkuti, M.D., Ph.D., Jennifer Nichols, D.O., Jay Schinfeld, M.D., Michael Sobel, D.O., and Larry Barmat, M.D.
This randomized controlled trial showed a significant improvement in embryo morphology with autologous endometrial coculture as compared with traditional culture media; however, clinical outcomes including live birth rate were similar between the groups.

 Case Reports
Natasha Gupta, M.D., Nirbhay Parashar, M.D., Richard Trester, M.D., and Josef Blankstein, M.D.
Cesarean section is considered the safest method of delivery for breech presentation but is also associated with birth traumas such as long bone fracture of the neonate.

Junhao Yan, M.D., Ph.D., Qian Zhang, M.D., Yanqin Chen, B.S.M., and Zi-Jiang Chen, M.D., Ph.D.
This case report documents the birth of an approximately normal offspring with mosaic karyotype 46,XX,[86]/46, XX,t(21;21)[14] to a 45,XY,t(21;21)(q10;q10) homologous Robertsonian translocation carrier.

 Checklist for Authors


The opinions and statements in this journal are those of the authors and are not attributable to the sponsor, publisher, editors or editorial board of JRM. Product dosages, indications and methods of use referred to in the papers and discussions reflect the authors' clinical experience or are derived from other professional sources.